Top 50 Biotech Companies in Los Angeles, CA

Did you know that the global biotech market was valued at $550.83 billion last year and is projected to grow to $23667.36 billion in a decade?
It’s becoming harder and harder to ignore the importance of biotech everywhere.
Los Angeles has always been the go-to place for entertainment and tech, but the reality is that there is much more to the city than Hollywood and tech startups.
In fact, Los Angeles has one of the fastest-growing biotech ecosystems we’ve seen in the last decade in the United States.
Los Angeles has not one or two, but three of the most prominent research universities in the United States. These being UCLA, USC, and Caltech. Los Angeles has become a big influence in different biotech research areas such as immunotherapy, gene editing, and biomaterial sustainability.
In this article, we’ll be going through 50 of the most important biotech companies in Los Angeles, from amazing startups with growth potential to global giants with years of experience under their belts.
This article will help you explore lesser-known biotech companies and get better insight from biotech giants who continue to innovate year after year.
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Our List of the Top 50 Biotech Companies in Los Angeles
We will divide this list into different sections ranging from the actual company size to the types of tools they use in their research.
Our team handpicked all 50 of these biotech companies from LA because they are all innovating and thriving in what they are trying to achieve.
Biotech Giants
All these Los Angeles-based companies thrive in creating commercial products, strong pipelines, and they have a direct global impact.
1. Amgen
Based in Thousand Oaks, Amgen isn’t only a giant in LA; it’s a worldwide powerhouse that is well-known for its biologics targeting cancer, cardiovascular disease, and inflammation. Their main goal is to serve patients and improve their quality of life in the process.
Just last year, they generated more than $33 billion in revenue from drugs such as Prolia, Repatha, Enbrel, Tepezza, and Kyprolis.
2. Kite Pharma
Santa Monica’s Kite Pharma is a well-known biotech company that focuses on CAR-T cell therapy, with an FDA-approved Yescarta and years’ worth of valuable oncology research. Their website is filled with amazing information that helps you learn more about them.
3. Puma Biotechnology
Puma Biotechnology primarily focuses on HER2-positive breast cancer research and has vast experience in different targeted therapies that have a close connection with their oncology research.
4. Acelryn (Merged with Alumis)
Acelryn is a well-known clinical-stage company that has been making leaps in its research for inflammatory diseases.
Alceryn is generally known for its exceptional work on the IL-17A inhibitor izokibep.
5. Capsida Biotherapeutics
Capsida Biotherapeutics is a gene therapy firm mainly focused on next-gen AAV capsid innovations that help treat different neurodivergent diseases efficiently and precise way.
If you want to learn even more about their projects and products, you can check their website.
6. Xencor
With their proprietary XmAb® platform, Xencor, the Pasadena-based biotech company focuses on engineering antibodies and cytokine therapies for both autoimmune and cancer diseases.
7. Arrowhead Pharmaceuticals
Arrowhead Pharmaceuticals is a famous Pasadena-based firm that primarily focuses on developing RNAi therapies that inhibit disease-causing genes across multiple conditions.
8. Atara Biotherapeutics
Atara Biotherapeutics is one of the leading LA-based biotech companies in off-the-shelf allogeneic T-cell immunotherapies. They also focus their work on both cancer and autoimmune diseases.
9. Enochian Biosciences (Renovaro)
Enochian Biosciences, also known as Renovaro, is a company that mainly focuses on gene-modified immune cells to counteract and treat cancer as well as other infectious diseases.
10. Capricor Therapeutics
Capricor Therapeutics’ main research focuses on regenerative medicine and exosome-based therapeutics for different muscular dystrophy and cardiac disorders.
Biotech Startups With High-Growth Potential
All of the LA-based biotech startup companies below are pushing the boundaries of science and medicine every month and continuing to innovate with creative and scalable technologies.
It’s no secret how difficult it is to go grow in the startup industry. Data shows us this every year. Despite that, these startups beat the odds and continue to grow as we speak.
11. Appia Bio
Appia Bio is a UCLA spinout that appeared and raised $52 million in Series A to advance and work on their “off-the-shelf” CAR-iNKT therapies. Said therapies are derived from stem cells and focus on targeting both hematologic and solid tumors.
12. Octant Bio
Octant Bio is an LA-based biotech company that is leveraging everything related to synthetic biology and AI to reengineer cellular circuits and protein interactions. This not only opens doors to new research opportunities, but it also advances the different precision drug discovery platforms.
13. Bionaut Labs
Bionaut Labs mainly focuses on the development of different injectable microrobots capable of navigating the brain’s complicated environment. This helps deliver different therapies with never-before-seen spatial control.
14. Kernel
Kernel’s wearables, such as their neuroimaging headsets (MEG/fNIRS), provide a less invasive way to monitor and interpret brain activity in real time. This not only helps neurology, but it also has different mental wellness applications.
15. Shoreline Biosciences Inc
Shoreline Biosciences Inc. is an LA-based biotech company that focuses on its proprietary cell therapy technology platform that is based on iPSC differentiation methods and complex genetic programming of the IL-15/CISH pathway for improved overall metabolic fitness.
16. Microscape
Microscape is an excellent LA-based startup that focuses on building 3D-printed microenvironments that replicate human tissue on a physical and chemical level.
This makes disease modeling and drug testing possible with zero animal or human testing.
Though there are very limited company updates on their most recent research, some publications suggest that high-throughput 3D scaffold printing capabilities will lead to their translational research.
17. Sanguine Biosciences
Sanguine Biosciences specializes in decentralized sample collections and logistic solutions that help improve overall clinical trial access and biomarker diversity across different regions.
18. Bone Biologics Corp.
Bone Biologics Corp develops protein-based bone graft replacements and injectables that help accelerate the healing process of various spinal and orthopedic procedures. Check their website if you want to learn more about how their project works.
19. Dalton Bioanalytics
Dalton Bioanalytics is a startup that focuses on high-throughput mass spectrometry. This helps enable precise proteomic analyses for different biomarker discovery and therapeutic monitoring.
20. Sequencing
Sequencing offers a plethora of DTC genetic sequencing services that are paired with AI-powered insights and different marketplace apps that help customize and understand your health, nutrition, and ancestry better.
Tools and Platforms for Diagnostics
These LA-based biotech companies focus on everything related to the creation of tools that facilitate how healthcare professionals diagnose different issues.
21. Beckman Coulter Diagnostics
With major labs in the LA metro area, Beckman Coulter Diagnostics develops and supplies different automated blood analyzers and clinical immunoassays to hospitals, clinics, and labs all over the world.
22. Thermo Fisher Scientific
Thermo Fisher Scientific is an LA-based regional operations company that supports local biotech R&D through sales, distribution of different lab equipment, reagents, services, and sequencing tools.
23. ALine Inc.
ALine Inc. primarily focuses on creating microfluidic platforms that ease and speed up the sampling process for miniaturized diagnostics. This enables portable assays and point-of-care testing.
24. ImaginAb
ImaginAb produces ImmuniPET tracer antibodies that help healthcare professionals have real-time imaging of T-cell infiltration and immune responses in oncology clinical trials.
25. Singlera Genomics
Singlera Genomics develops epigenetic liquid biopsy tests for early non-aggressive or invasive detection of multiple cancers by analyzing a patient’s DNA methylation signatures.
26. BioLegend (Revvity)
Biolegend, also known as Revvity, is an LA-based biotech manufacturer that mainly focuses on the creation of quality antibodies, flow cytometry reagents, and immunology kits for genomics research in biopharma and academic labs all over the world.
27. Prodeon
Prodeon combines both metabolomics and AI-driven data analysis to create next-gen diagnostic assays for early disease detection. This is all part of a next-gen diagnostic toolkit that specifically targets personalized medicine.
28. Ixcela
Ixcela is an LA-based biotech company that measures internal biomarkers such as gut permeability to help generate a personalized and actionable health and wellness plan for their customers.
Exclusive Biotech Manufacturers and Service Providers
These LA-based biotech companies are entirely focused on creating and providing services for both consumers and laboratories around the world.
29. FUJIFILM Diosynth Biotechnologies
FUJIFILM Diosynth Biotechnologies is a worldwide CDMO with a large-scale facility in LA that helps support biologic and gene therapy manufacturing under different GMP standards.
30. Theragent
Theragent is an LA biotech manufacturer that provides cell and gene therapy development out of Arcadia. This not only includes the product itself but also the process design and the scale-up process.
31. AGC Biologics
AGC Biologics is an LA-based biotech company that manufactures protein and viral-based therapies for clinics and hospitals all over the world. Check their website if you want to learn more about their projects.
32. IQVIA
IQVIA is a biotech company that offers different services such as trial management, regulatory consulting, and biostatistics tailored to biotech firms all over the world that need an efficient trial execution.
33.VintaBio
VintaBio is a relatively new contract manufacturer that mainly focuses on the supply of different clinical-grade gene and cell therapies for mid-stage programs. This is a very interesting company that has the attention of different investors all over the world.
34. Zymo Research
Zymo Research is an LA-based biotech company that delivers kits and reagents for epigenetics, DNA/RNA purification, and microbiome correlative research.
They mainly service and work with other biotech companies from both LA and Orange County.
35. Aviva Systems Biology
Aviva Systems Biology is a biotech manufacturer that produces proprietary antibodies, ELISA kits, and assay reagents for proteomics and diagnostics research.
36. Bio-Check Inc.
Bio-Check Inc. is a great LA-based biotech company that designs and manufactures in vitro assays that meet domestic and international regulatory standards. if you want to learn more about this startup, you can check their website.
37. BioRegentech
BioRegentech is a biotech company that provides hospitals and clinics with a customized bioprocess development and biologics scale-up services for their research.
38. OrthogenRx
OrthogenRx is an LA biotech company that creates injectable biologic products that effectively treat musculoskeletal conditions like osteoarthritis. They mainly source and ship their products to different cities in California.
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Agricultural Biotech, FoodTech, and Biomaterials
These biotech companies mainly focus on the sustainability of food and its efficacy during different stages of a human lifespan.
39. AgriProtein (InnovaFeed)
AgriProtein, also known as InnovaFeed, is an LA-based biotech company that uses black soldier fly larvae to transform food waste into high-nutrient animal feed called “MagMeal.”
This not only helps sustain the ever-growing animal feed needs, but it also solves a major problem like organic food waste in an efficient way.
Long gone are the days of fishmeal and palm oil dependency for agriculture. With this product, we can expect to see a complete circular economy for agriculture in the near future.
Their mulitlingual website offers visitors the opportunity to lean about their products in both English and French
40. Bolt Threads
Bolt Threads is a biotech company that produces next-gen biomaterials like mushroom-based leather and a synthetic spider silk for a more sustainable way to use silk for clothing.
41. Beyond Meat
Beyond Meat is one of LA’s pioneers in plant-based meat substitutes. They use molecular biology and formulas to mimic the real taste of meat down to the texture without it having any meat anywhere. Despite taking a hit in workforce and revenue after the COVID pandemic in 2020, they are still the leading biotech company for sustainable protein innovation.
42. Clara Foods (The EVERY Company)
Clara Foods, now known as The EVERY Company, is a biotech company that produces animal-free egg proteins through its proprietary fermentation that is used in food, pharmaceuticals, and more.
43. Pivot Bio
Pivot Bio is an LA-based company that creates nitrogen-fixing bacteria that is used to reduce the usage of pesticides and synthetic fertilizers on grain crops. This not only provides a better product overall, but it lowers agriculture’s carbon footprint almost immediately.
44. Terviva
Terviva is a biotech brand that focuses on growing pongamia trees that produce sustainable oils used in both food and bioproducts.
Not only that, they also provide biomass feedstock for energy.
45. Synthetic Genomics (Viridos)
Synthetics Genomics, also known as Viridos, is an LA biotech company that uses algae metabolic engineering to create different products, such as biofuels, bioplastics, and carbon sequestration platforms.
Academic Spinouts
Last but not least, we have the academic section of LA biotech companies.
All of these are always pushing the boundaries of biotech with their advanced research every year.
46. Lactiga Therapeutics
Lactiga Therapeutics collects and harnesses human milk oligosaccharides and glycoproteins to create novel immune-modeling therapies and microbiome products on a large scale.
47. NeuroSigma
NeuroSigma is an LA biotech company that creates noninvasive neuromodulation devices that target the trigeminal nerve.
These devices help treat both epilepsy and ADHD. Early clinical data have shown a significant reduction in seizure frequency and an improved attention span.
The company will enter its most important trials to test and validate its efficacy soon.
48. Cellmic (Holomic)
UCLA-derived startup Cellmic is producing smartphone-integrated cell imaging systems for point-of-care disease diagnostics. They are still early in research and development, but it is definitely an LA-based biotech company to keep an eye on.
49. ImmunityBio
ImmunityBio is an LA biotech company founded by the great Dr. Patrick Soon-Shiong. They develop advanced and revolutionary cancer immunotherapies and novel oncolytic vaccines.
50. Aracari Biosciences
Aracari Biosciences is a biotech company that creates vascularized 3D tissue-on-chip platforms that help other companies test drugs and integrate medicine.
Despite being in different fields within biotech, all of these companies share something in common. They all have great minimalist websites that help anyone understand exactly what they offer in a matter of seconds.
Having an innovative product that could change people’s lives is difficult to market if people can’t learn more about it anywhere.
Get Your Custom Biotech Website to the Next Level With Blacksmith
A custom website is the perfect way to not only explain what your product or service does, but it can also help you close sales without having to do anything.
But we’re not going to lie to you and say that creating a website is a fast endeavor.
On the contrary, creating an exceptional website takes a lot of time and planning, especially for a biotech company that needs everything to look its best for potential investors and big partnerships.
We get it, creating a website from scratch might seem like a big project that you might not have the time for, especially with all the work that your biotech company requires every day.
So what now?
That’s where we come in. Here at Blacksmith, we’re experts at creating custom websites that help biotech companies showcase their innovations and products in a way that entices visitors to learn more about them.
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